Method of identifying molecules that regulate FGF activity

Details Method of identifying molecules that regulate FGF activity Method of identifying molecules that regulate FGF activity

1997-04-23

1999-04-06

Wilson, James O.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 691, 435 694, 4351723, 424 173, 4241581, 530399, 536 11, 536 41, 536 21, 536123, 53612313, G01N 33567

Patent

active

058916555

ABSTRACT:
Disclosed are fibroblast growth factor (FGF) binding and FGF receptor activation, and a method of identifying small molecular weight compounds that interact with FGF to modulate its activity such as, e.g., activators and inhibitors. Illustrative small oligosaccharides, namely di- and tri-saccharides, are shown to be effective modulators of FGF binding and FGF receptor activation.

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