Method of identifying molecules that regulate FGF activity

Details Method of identifying molecules that regulate FGF activity Method of identifying molecules that regulate FGF activity

1995-03-15

1998-03-31

Wilson, James O.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 54, 435 721, 435 691, 4351723, 4352402, 424 173, 4241581, 536 11, 536 41, 536 21, 536123, 53612313, A61K 4736, A61K 31715, A61K 31725, C07H 306

Patent

active

057338930

ABSTRACT:
Disclosed are fibroblast growth factor (FGF) binding and FGF receptor activation, and a method of identifying small molecular weight compounds that interact with FGF to modulate its activity such as, e.g., activators and inhibitors. Illustrative small oligosaccharides, namely di- and tri-saccharides, are shown to be effective modulators of FGF binding and FGF receptor activation.

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