Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Chemical analysis
Reexamination Certificate
2006-07-31
2010-11-02
Steadman, David J (Department: 1656)
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Chemical analysis
C703S011000
Reexamination Certificate
active
07826982
ABSTRACT:
The preferred embodiments generally relate to methods and compositions that affect the GTP-binding activity of members of the Rho family GTPases, preferably Rac (Rac1, Rac2 and/or Rac3), such compositions include compounds that modulate the GTP/GDP exchange activity, along with uses for the compounds including screening for compounds which recognize Rac GTPase, and methods of treating pathological conditions associated or related to a Rho family GTPase, including Rac. The preferred embodiments also relate to methods of using such compounds, or derivatives thereof, e.g., in therapeutics, diagnostics, and as research tools.
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Nassar Nicolas
Skowronek Karlheinz R.
Zheng Yi
Children's Hospital Medical Center
Knobbe Martens Olson & Bear LLP
Steadman David J
The Research Foundation of State University of New York
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