Method of identifying hairpin DNA probes by partial fold...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C536S022100, C536S023100, C536S024300

Reexamination Certificate

active

07598034

ABSTRACT:
Method of identifying molecular beacons in which a secondary structure prediction algorithm is employed to identify oligonucleotide sequences within a target gene having the requisite hairpin structure. Isolated oligonucleotides, molecular beacons prepared from those oligonucleotides, and their use are also disclosed.

REFERENCES:
patent: 5215899 (1993-06-01), Dattagupta
patent: 5556749 (1996-09-01), Mitsuhashi et al.
patent: 5925517 (1999-07-01), Tyagi et al.
patent: 6114121 (2000-09-01), Fujiwara et al.
patent: 6194155 (2001-02-01), Cohen
patent: 6251588 (2001-06-01), Shannon et al.
patent: 6277607 (2001-08-01), Tyagi et al.
patent: 6312906 (2001-11-01), Cass et al.
patent: 6355437 (2002-03-01), Neri et al.
patent: 6365729 (2002-04-01), Tyagi et al.
patent: 6380377 (2002-04-01), Dattagupta
patent: 7070933 (2006-07-01), Browne
patent: 2003/0013109 (2003-01-01), Ballinger et al.
patent: 2003/0054346 (2003-03-01), Shannon et al.
patent: 2003/0143535 (2003-07-01), Lyamichev et al.
patent: 00/43552 (2000-07-01), None
Zuker et al., Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information. Nucleic Acids Research 9(1) : 133-148 (1981).
Bonnet et al., “Thermodynamic Basis of the Enhanced Specificity of Structured DNA Probes,”Proc. Natl. Acad. Sci. USA96:6171-6176 (1999).
Du et al., “Hybridization-Based Unquenching of DNA Hairpins on Au Surfaces: Prototypical “Molecular Beacon” Biosensors,”J. Am. Chem. Soc. 125:4012-4013 (2003).
Dubertret et al., “Single-Mismatch Detection Using Gold-Quenched Fluorescent Oligonucleotides,”Nat. Biotech. 19:365-370 (2001).
Broude, “Stem-loop Oligonucleotides: A Robust Tool for Molecular Biology and Biotechnology,” Trends in Biotechnology 20(6):249-56 (2002).
Elsayed et al., “Development and Validation of a Molecular Beacon Probe-Based Real-Time Polymerase Chain Reaction Assay for Rapid Detection of Methicillin Resistance inStaphylococcus aureus,” Arch. Pathol. Lab. Med. 127:845-9 (2003).
Kushon et al., “Effect of Secondary Structure on the Thermodynamics and Kinetics of PNA Hybridization to DNA Hairpins,” J. Am. Chem. Soc. 123(44):10805-13 (2001).
Park et al., “Rapid Identification of Candida dubliniensis Using a Species-Specific Molecular Beacon,” Journal of Clinical Microbiology 38(8):2829-36 (2000).
Riccelli et al., “Hybridization of Single-stranded DNA Targets to Immobilized Complementary DNA Probes: Comparison of Hairpin Versus Linear Capture Probes,” Nucleic Acids Research 29(4):996-1004 (2001).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of identifying hairpin DNA probes by partial fold... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of identifying hairpin DNA probes by partial fold..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of identifying hairpin DNA probes by partial fold... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4097575

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.