Method of identifying compounds that regulate the binding of M.

Details Method of identifying compounds that regulate the binding of M. Method of identifying compounds that regulate the binding of M.

1997-04-09

1999-12-21

McKelvey, Terry

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

G01N 33566

Patent

active

06004764&

ABSTRACT:
sigF is a gene that controls M. tuberculosis latency. A diagnostic test for latent tuberculosis involves detecting M. tuberculosis sigF in clinical specimens. Two genes orfX and orfY regulate sigF expression and sigF activity. M. tuberculosis sigF, orfX, and orfY are used in screening methods for potential therapeutic agents which regulate the growth of M. tuberculosis.

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