Method of identifying agents that affect human NHE3

Details Method of identifying agents that affect human NHE3 Method of identifying agents that affect human NHE3

1996-07-10

1999-02-16

Ulm, John

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 691, 536 235, 530350, C12Q 168, C12N 1512, C07K 14435

Patent

active

058719199

ABSTRACT:
The present invention teaches a method of identifying agents that affect NHE3. Specifically, these methods comprise the steps of obtaining DNA encoding all or a portion of human NHE3, introducing that DNA into a recipient host cell whereby the host cell can perform Na+/H+ exchange, applying agents to the host cell, and assessing whether the agents affect Na+/H+ exchange.

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