Method of identifying activated T-cells

Details Method of identifying activated T-cells Method of identifying activated T-cells

1996-01-26

1998-10-13

Jones, W. Gary

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 6, 536 2433, C12P 1934, C12Q 168

Patent

active

058210911

ABSTRACT:
A method of identifying the presence of activated T-cells in a sample containing a plurality of different cell types is disclosed. The method includes the detection of polynucleotide sequences selectively expressed in activated T-cells.

REFERENCES:
Kofler (1992) Mol. Immunol. 29:161-66.
Goring (1992) Exp. Eye Res. 54:785-95.
Takahashi (1993) FEBS Lett. 319:45-8.
Kwan et al. (1994) Cytogenet. Cell Genet. 67:341 abstract.
Boultwood, J., et al., "The 5q.sup.- Syndrome," Blood 84(10) :3253-3260 (1994).
Dolganov, G., et al., "Coexpression of the Interleukin-13 and Interleukin-4 Genes Correlates with Their Physical Linkage in the Cytokine Gene Cluster on Human Chromosome 5q23-32," Blood 87(8):3316-3326 (1996).
Hays, S.L., et al., "Complex Formation in Yeast Double-Strand Break Repair: Participation of Rad51, Rad52, Rad55, and Rad57 Proteins," Proc. Natl. Acad. Sci. USA 92:6925-6929 (1995).
Kinzler, K.W., et al., "Identification of a Gene Located at Chromosome 5q21 That is Mutated in Colorectal Cancers," Science 251: 1366-1370 (1991).
Kinzler, K.W., et al., "Identification of FAP Locus Genes from Chromosome 5q21," Science 253:661-664 (1991).
LeBeau, M.M., et al., "Cytogenetic and Molecular Delineation of the Smallest Commonly Deleted Region of Chromosome 5 in Malignant Myeloid Diseases," Proc. Natl. Acad. Sci. USA 90:5484-5488 (1993).
Lengyel, P., "Tumor-Suppressor Genes: News About the Interferon Connection," Proc. Natl. Acad. Sci. USA 90:5893-5895 (1993).
Morgan, J.G., et al., "The Selective Isolation of Novel cDNAs Encoded by the Regions Surrounding the Human Interleukin 4 and 5 Genes," Nuc. Acids Res. 20(19) :5173-5179 (1992).
Nagarajan, L., et al., "Consistent Loss of the D4S89 Locus Mapping Telomeric to the Interleukin Gene Cluster and Centromeric to EGR-1 in Patients with 5q Chromosome," Blood 83(1) :1994).
Neuman, W.L., et al., "Chromosomal Loss and Deletion are the Most Common Mechanisms for Loss of Heterozygosity from Chromosomes 5 and 7 in Malignant Myeloid Disorders," Blood 79(6) :1501-1510 (1992).
Solomon, E., et al., "Chromosome Aberrations and Cancer," Science 254:1153-1160 (1991).
Weinberg, R.A., "Tumor Suppressor Genes," Science 254:1138-1146 (1991).

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