Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2009-08-03
2011-10-04
Whisenant, Ethan C (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007100, C435S283100, C536S023100, C536S024300
Reexamination Certificate
active
08029994
ABSTRACT:
A method of identifying target analytes in a sample, particularly a biological sample, comprising the steps of putting a plurality of target analytes, bound to a common luminescent marker, in contact with a plurality of molecular probes immobilized on a support, each of said molecular probes being capable of complementary binding to a respective target analyte, if said target analyte is present in the sample, providing to said support an excitation radiation and detecting an emission radiation coming from said support as a result of at least one complementary binding event, characterized by the fact that:said support comprises a plurality of photonic crystal resonators, at least two of said resonators being characterized by different resonance wavelengths;each of said molecular probes being fixed to a respective resonator; and by the fact thatthe identification of at least one target analyte is carried out through the analysis of the total emission spectrum coming from said plurality of photonic crystals resonators, in order to detect possible wavelength resonance peaks generated as a result of the binding of said target analyte, bound to the common luminescent marker, to one or more of said molecular probes.
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Aoki Kanna
Arakawa Yasuhiko
Cingolani Roberto
De Vittorio Massimo
Martiradonna Luigi
Consiglio Nazionale Delle Ricerche-INFM Istituto Nazion
Sughrue & Mion, PLLC
Whisenant Ethan C
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