Method of identifying a nucleic acid using triple helix formatio

Details Method of identifying a nucleic acid using triple helix formatio Method of identifying a nucleic acid using triple helix formatio

1997-12-18

2000-02-22

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 911, 536 293, 536 2431, 536 2432, C12Q 168, C12P 1934, C07H 2100

Patent

active

060278935

ABSTRACT:
A method for determining a nucleic acid A, comprising the formation of a complex, including two molecules capable of hybridizing to A and of participating in formation of a triplex structure with an additional nucleic acid or nucleic acid analogue is useful for sensitive and specific determination.

REFERENCES:
Orum et al. Biotechniques vol. 19, No. 3, 1995.
International Publication No. WO 92/11390 published Jul. 9, 1992.
International Publication No. WO 93/06240 published Apr. 1, 1993.
International Publication No. WO 95/08556 published Mar. 30, 1995.
International Publication No. WO 95/14706 published Jun. 1, 1995.

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