Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2007-01-30
2007-01-30
Weber, Jon (Department: 1653)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C435S007100, C435S007900, C530S350000
Reexamination Certificate
active
10768158
ABSTRACT:
We claim a methods for identifying a compound capable of treating a pain or a painful disorder state comprising combining the test compound with the polypeptide of SEQ ID NO:2, and detecting binding of said test compound to said polypeptide thereby identifying a compound that binds to said polypeptide.
REFERENCES:
patent: WO 00/14251 (2000-03-01), None
patent: WO 02/18541 (2002-03-01), None
Nakamura et al. (2003) Steroid sulfatase and estrogen sulfotransferase in the atherosclerotic human aorta. Am. J. Pathol. vol. 163, No. 4, pp. 1329-1339.
Nagata et al. (2000) Pharmacogenetics of sulfotransferase. Annu. Rev. Pharmacol. Toxicol. vol. 40, pp. 159-176.
Oliveras et al. (1996) Picrotoxin produces a “central” pain-like syndrome when microinjected into the somato-motor cortex of the rat.. Physiol. Behav. vol. 60, No. 6, pp. 1425-1434.
Majewska et al. (1990) The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor. Brain Res. vol. 526, No. 1, pp. 143-146.
Baek, et al., “Overexpression of Arylsulfate Sulfotransferase as Fusion Protein with Glutathione S-Transferase”, Protein Expression and Purification 11:257-262 (Dec. 1997).
Alam, et al., “Platelet sulphotransferase activity, plasma sulphate levels and sulphation capacity in patients with migraine and tension headache”, Cephalalgia 17:761-764 (Nov. 1997).
Eliasof Scott D.
Karicheti Venkateswarlu
Silos-Santiago Inmaculada
Banner & Witcoff , Ltd.
Bayer Healthcare AG
Liu Samuel W.
Weber Jon
LandOfFree
Method of identifying a compound capable of treating a pain... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of identifying a compound capable of treating a pain..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of identifying a compound capable of treating a pain... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3796528