Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1992-03-10
1993-04-06
Robinson, Douglas W.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
C12P 1716
Patent
active
052003299
ABSTRACT:
Incubation of 3-[(4,7-dichlorobenzoxazol-2-yl)methyl]amino-5-ethyl-6-methyl-2-(1H)-pyrid inone ##STR1## with a preparation from mammalian organ yields as biotransformation products the 5-(1-hydroxy)ethyl and 6-hydroxymethyl analogs. These products are useful in the prevention or treatment of infection by HIV and the treatment of AIDS.
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Balani Suresh K.
Kauffman Laura R.
Theoharides Anthony D.
Caruso Charles M.
Merck & Co. , Inc.
Meredith Roy D.
Robinson Douglas W.
Saucier S.
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