Method of hormonal treatment for menopausal or post-menopausal d

Details Method of hormonal treatment for menopausal or post-menopausal d Method of hormonal treatment for menopausal or post-menopausal d

1984-07-24

1989-05-02

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

A61K 3156

Patent

active

048268313

ABSTRACT:
A method of hormonally treating menopausal (including perimenopausal and post-menopausal) disorders in women, a composition, and a multi-preparation pack therefor. The administrative regimen to which the pack is particularly adapted comprises continuously and uninterruptedly administering a progestogen to a woman while cyclically administering an estrogen by using a repetitive dosage regimen. This regimen calls for administering the estrogen continuously for a period of time between about 20 and about 120 days, followed by terminating administering the estrogen for a period of time between about 3 and about 7 days. Alternatively, both the progestogen and estrogen may be administered for the full treatment period without interruption. The regimen avoids many of the problems associated with the administration of estrogen alone or with progestogen administered according to conventional regimens, and also avoids problems associated with such conventional regimens by maintaining the estrogen and progestogen at low daily dosage levels of between 0.005 mg and 2.5 mg estrogen and 0.25 mg and 30 mg progestogen.

REFERENCES:
patent: 3836651 (1974-09-01), Rudel et al.
patent: 3957982 (1976-05-01), Lachnit-Fixson et al.
patent: 4425339 (1984-01-01), Pitchford
Magglestone et al., Acta, Obstet. Gynecol. Scand., 59:(1980), pp. 327-329.
Chemical Abstracts, vol. 83, No. 9, Sep. 1, 1975, p. 142, abstract No. 72528 q.
Unlisted Drugs, vol. 22, No. 10, Oct. 1970, p. 149; vol. 25, No. 10, Oct. 1973, p. 160a; vol. 26, No. 11, Nov. 1974, p. 170b; vol. 27, No. 8, Aug. 1975, p. 130g; vol. 28, No. 2, Feb. 1976, p. 26j; vol. 29, No. 3, Mar. 1977, p. 41g.

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