Method of highly concentrated cultivation of yeasts

Details Method of highly concentrated cultivation of yeasts Method of highly concentrated cultivation of yeasts

1979-01-22

1981-08-18

Penland, R. B.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

435256, 435800, 435804, 435813, 435940, C12N 116

Patent

active

042847249

ABSTRACT:
A broth containing yeast cells is continuously or intermittently removed from a fermentor. Then, yeast cells are separated from the filtrate using a cell separator, or further washed with water. Then, the yeast cells so obtained are recycled to the fermentor, whereby yeasts are cultivated at a high cell concentration of from 6% to about 20% based on dry weight. As discussed herein, by removing the filtrate from the cultivation system, there is no accumulation of metabolites and salts prohibiting the cultivation of yeasts, and further the growth of miscellaneous microorganisms which interfere with yeast cell growth, is surprisingly suppressed.

REFERENCES:
patent: 3186917 (1965-06-01), Gerhardt et al.
patent: 3418208 (1968-12-01), Coty
patent: 3847739 (1974-11-01), Champagnat et al.
patent: 3887435 (1975-06-01), Nakamura et al.
patent: 3929578 (1975-12-01), Urakami
patent: 3940492 (1976-02-01), Ehnstrom
patent: 3966554 (1976-06-01), Vass et al.
patent: 4028182 (1977-06-01), Zajic et al.
patent: 4062727 (1977-12-01), Srinivasan et al.
Gerhardt et al., "Dialysis Flask for Concentrated Culture of Microorganisms", J. Bacteriology vol. 86, pp. 919-928, (1963).

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