Method of hastening cervical ripening

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C514S002600, C530S399000, C530S350000

Reexamination Certificate

active

06946442

ABSTRACT:
The use of an agent for controlling vascular permeability within the cervix is disclosed for controlling cervical ripening. To hasten cervical ripening, the agent is one which increases vascular permeability and is selected from VEGF121, VEGF145, VEGF165, VEGF189, VEGF206, a smaller, active VEGF fragment, and placenta growth factor (PlGF). If cervical ripening is to be delayed, the agent is one which reduces vascular permeability, e.g. a VEGF receptor antagonist or antibody. The agents of the present invention can be used as a means of managing labor.

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