Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-11-28
2006-11-28
Johannsen, Diana (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200, C536S023200, C536S023500
Reexamination Certificate
active
07141373
ABSTRACT:
Disclosed is a method for determining haplotypes useful for large-scale genetic analysis, within a genomic reference sequence of interest, for a human subpopulation. The method can applied to statistically evaluating the genotypes of subjects for any statistically significant association with a phenotype of interest, such as insulin resistance or coronary artery disease. Thus, also disclosed are a method of detecting a genetic predisposition in a Mexican-American human subject for developing insulin resistance and methods of detecting a lower than normal risk in a Mexican-American human subject for developing insulin resistance or coronary artery disease.
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Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, L
Goodarzi Mark O.
Guo Xiuqing
Hsueh Willa A.
Raffel Leslie J.
Rotter Jerome I.
Cedars-Sinai Medical Center
Johannsen Diana
Kapushoc Stephen
Perkins Coie LLP
The Regents of the University of California
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