Method of growing vertebrate skin in vitro

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435367, 435371, 435398, 435402, 673 15, C12N 500, C12N 502, A61F 210

Patent

active

056863039

ABSTRACT:
A method of growing complete vertebrate skin in vitro, which comprises obtaining a segment of vertebrate skin, positioning the skin segment in an artificial cell-growth medium containing sufficient nutrients to maintain growth of cells of the skin, and subjecting the skin segment to stretching forces while the skin segment is in the medium. Skin produced by the method and an apparatus for carrying out the method are also part of the present invention.

REFERENCES:
patent: 3640279 (1972-02-01), Brown et al.
patent: 4673649 (1987-06-01), Boyce et al.
Argenta, L.C. et al., (1983) "The Use of Tissue Expansion in Head and Neck Reconstruction," Ann. Plast. Surg. 11:31-37.
Argenta, L.C. (1984) "Controlled Tissue Expansion in Reconstructive Surgery," Brit. J. Plas. Surg. 37:520-529.
Hiernickel, H. (1985) "An Improved Method For In Vitro Perfusion of Human Skin," British Journal of Dermatology 112:299-305.
Carney, S.A. (1986) "Generation of Autograft; The State of the Art," Burns 12:231-235.
Eldad, A. et al., (1987) "Cultured Empithelium as a Skin Substitute," Burns 13(3):173-180.
Gallico III, G.G. (1990) "Biologic Skin Substitutes," Clinics In Plastic Surgery 17(3):519-526.
Nanchahal, J. and C.M. Ward, (1992) "New Grafts For Old? A Review of Alternatives to Autologous Skin," British Journal of Plastic Surgery 45:354-363.
Dennis, L.W. (1992) "Tissue Cultured Skin Grafts," Journal of Burn Care & Rehabilitation 13(1):93-94.
Arons, J.A. et al., (1992) "The Surgical Applications and Implications of Cultured Human Epidermis: A Comprehensive Review," Surgery 111(1):4-11.
Greenwald, D.P. et al., (1992) "Full-Thickness Skin Wound Explants in Tissue Culture: A Mechanical Evaluation of Healing," Plastic and Reconstructive Surgery 90(2):289-294.
Wong, L. and A.M. Munsten, (1993) "New Techniques in Burn Wound Management," Surgical Clinics of North America 73(2):363-371.
Kirsner, R.S. et al., (1993) "The Biology of Skin Grafts," Arch Dermatol 129:481-483.
Teepe, R.G.C. et al., (1993) "Randomized Trial Comparing Cryopreserved Cultured Epidermal Allografts With Tulle-Gras in the Treatment of Split-Thickness Skin Graft Donor Sites," The Journal of Trauma 35(6):850-854.
Tanner, James C. et al. (1964) "Plastic and Reconstructive Surgery," 34:287-292.
Tanner, James C. et al. (1966) "American Journal of Surgery," 111:543-547.
Tanner, James C. et al. (1969) "Plastic and Reconstructive Surgery," 44:504-506.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of growing vertebrate skin in vitro does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of growing vertebrate skin in vitro, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of growing vertebrate skin in vitro will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1228187

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.