Method of grinding pharmaceutical substances

Details Method of grinding pharmaceutical substances Method of grinding pharmaceutical substances

1994-01-12

1996-05-21

Eley, Timothy V.

Solid material comminution or disintegration

Processes

By utilizing kinetic energy of projected or suspended material

241 21, 241 22, 241170, 241184, B02C 1720, B02C 2318

Patent

active

055181872

ABSTRACT:
A method of preparing particles of a drug substance or diagnostic imaging agent which comprises grinding the drug substance or imaging agent in the presence of grinding media comprising a polymeric resin. The method provides particles exhibiting reduced contamination.

REFERENCES:
patent: 1807383 (1931-05-01), Carnahan
patent: 3104068 (1963-09-01), Castelli et al.
patent: 4404346 (1983-09-01), Pirotta
patent: 4974368 (1990-12-01), Miyamoto
patent: 5066335 (1991-11-01), Lane
patent: 5066486 (1991-11-01), Kamen
patent: 5145684 (1992-09-01), Liversidge
patent: 5320284 (1994-06-01), Nishida et al.

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