Method of grafting genetically modified cells to treat defects,

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

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424 9321, 4351723, 435948, 514 44, 935 62, 935 70, A61K 4800, A61K 3100, C12N 1500, C12N 500

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056501480

ABSTRACT:
Methods of genetically modifying donor cells by gene transfer for grafting into the central nervous system to treat defective, diseased or damaged cells are disclosed. The modified donor cells produce functional molecules that effect the recovery or improved function of cells in the CNS. Methods and vectors for carrying out gene transfer and grafting are described.

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