Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2005-07-19
2005-07-19
Leffers, Gerry (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S455000, C435S325000, C435S366000, C435S372000, C435S375000, C435S006120, C435S320100, C536S023100
Reexamination Certificate
active
06919209
ABSTRACT:
This invention relates to a method for transducing extremely primitive hematopoietic stem cells with high efficiency, using an adeno-associated vector. This vector stably transforms highly primitive CD34+++CD38=cells which reside in a quiescent state and retain to a larger extent the ability to repopulate the hematopoietic system.
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Chatterjee Saswati
Fisher-Adams Grace
Wong Christie
Wong, Jr. Kamehameha K.
City of Hope
Leffers Gerry
Rothwell Figg Ernst & Manbeck P.C.
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