Method of gasifying and agitating a fermentation culture

Details Method of gasifying and agitating a fermentation culture Method of gasifying and agitating a fermentation culture

1978-02-09

1980-05-20

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435243, 435313, 435314, 435818, 435837, C12N 120

Patent

active

042040426

ABSTRACT:
The invention relates to a method of and an apparatus for enabling a micro-organism culture to be gasified and agitated so as to accelerate its growth. The culture is contained in a fermenter which comprises two containers C.sub.1 and C.sub.2 which communicate with one another in their upper and lower regions. The method consists of injecting sterile air in the form of bubbles discontinuously at the base of one C.sub.1 of the containers with injection periods of predetermined length alternating with non-injection periods at a predetermined frequency. This sequential infeed of air produces a surging or pulsating effect in the culture which, for a given consumption of air, very considerably increases the density of micro-organism achieved at the end of a given period of time. The invention is applicable to the cultivation of all aerobic micro-organisms:cells, fungi, bacteria, etc.

REFERENCES:
patent: 3002894 (1961-10-01), Rungaldier et al.
patent: 3384553 (1968-05-01), Caslavsky et al.
patent: 3732148 (1973-05-01), Franckowiak et al.
patent: 3857757 (1974-12-01), Herrick et al.
patent: 3929582 (1975-12-01), Kellner
patent: 3957585 (1976-05-01), Malick
patent: 3982998 (1976-09-01), Hitzman et al.

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