Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or...
Reexamination Certificate
2006-07-11
2006-07-11
Lankford, Jr., Leon B. (Department: 1651)
Chemistry: molecular biology and microbiology
Differentiated tissue or organ other than blood, per se, or...
C435S373000, C435S375000, C435S325000, C435S397000, C435S369000, C435S371000, C424S093100, C424S093700
Reexamination Certificate
active
07074552
ABSTRACT:
A method for constructing a stable bioactive mammalian embryonic kidney is described herein. A kidney so constructed requires no artificial support, nor porous man made membranes or tubing to effectuate its biological function of filtering body fluids. A single donor embryonic kidney, or fragment thereof, can produce a great number of functional kidneys suitable for treating subjects with various kidney disorders. It is anticipated that said in vitro produced kidney would be less, or not at all, antigenic when transplanted into a subject, because of its embryonic character and artificial propagation in culture. This method of producing a functional organ can be useful in cloning other organ structures containing inducible epithelial tissues.
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Nigam Sanjay Kumar
Qiao Jizeng
Sakurai Hiroyuki
Buchanan Ingersoll LLP
Ford Allison M.
Lankford , Jr. Leon B.
The Regents of the University of California
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