Method of forming prosthetic devices

Details Method of forming prosthetic devices Method of forming prosthetic devices

1985-12-26

1987-06-02

Silverberg, Sam

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Particulate or unit-dosage-article base

623 1, 4274301, A61F 100, A61B 1711

Patent

active

046702865

ABSTRACT:
A sterile shaped prosthetic device, suitable for insertion into a mammalian body, is at least partly composed of a bioresorbable material that is digestible by macrophages, its surface properties favor the attachment and adhesion of fibroblast cells capable of producing collagen for organized connective tissues, and the material itself or its degradation products can induce in vivo the formation of new capillary vessels (termed a "vasotropic" effect herein). Preferred prosthetic devices have through passages, the interspatial dimensions which are sufficient to permit several layers of mammalian cells to form within each passage. The invading fibroblast cells commence formation of collagen leading to connective tissue while macrophages and extracellular enzymes degrade the material, and newly formed capillary vessels penetrate the prosthesis and provide blood containing oxygen and nutrients which further the formation of organized tissue around as well as within the prosthetic device.

REFERENCES:
patent: 3272204 (1966-09-01), Artandi
patent: 3425418 (1969-02-01), Chvapil
patent: 3620218 (1971-11-01), Schmitt
patent: 3883901 (1975-05-01), Coquard
patent: 4032993 (1977-06-01), Coquard
patent: 4074366 (1978-02-01), Capozza
patent: 4137921 (1979-02-01), Okuzumi
patent: 4208511 (1980-06-01), Shalaby

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