Method of forming hydrogel particles having a controlled size us

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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424489, 424490, 424493, 424496, 424499, 424500, 4284022, 264 41, 264 43, 514 54, A61K 9127, B01J 1302

Patent

active

056268700

ABSTRACT:
A method of fabricating hydrogel particles within liposomes, which entails: a) encapsulating an effective amount of each of one or more hydrogel substances and one or more release agents in liposomes in a liquid medium, b) removing any unencapsulated hydrogel substances and release agents from the liquid medium, c) adding initiator to the liquid medium and into the liposomes, thereby initiating reaction of the one or more hydrogel substances, whereby hydrogel particles are formed in the liposomes, and d) removing any extra-liposomal initiator from the medium.

REFERENCES:
patent: 4192900 (1980-03-01), Cheng
patent: 4520178 (1985-05-01), Sakata
patent: 4839111 (1989-06-01), Huang
patent: 5104736 (1992-04-01), Wallach

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