Method of forming closure system for medical liquid container

Package making – Interrelated or safety controls

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Details

53 37, 53 41, 53 42, B65B 5306, B65B 4300, B65B 728, B67B 320

Patent

active

040154017

ABSTRACT:
A medical liquid bottle having a threaded neck of one thermoplastic material is blow-molded at pressures of 50 to 150 psi (3.52 to 10.1 kg/cm.sup.2) so there is a low amount of internal stress in the neck. A cap of a different thermoplastic material is injection molded at pressures of 5,000 to 20,000 psi (352 to 1,410 kg/cm.sup.2) producing a very high internal stress in this cap. After liquid has been placed in the bottle and the cap assembled to the neck, the bottle with the combined cap and neck are stress relieved by subjecting to steam sterilization at 240.degree. F. to 260.degree. F. (116.degree. C. to 127.degree. C.). This causes the cap to shrink more than the neck and to form a bacteria-tight thermoplastic-to-thermoplastic hermetic seal. Despite this very tight hermetic seal the closure is openable with an unexpectedly low unscrewing torque of 10 to 30 inch-pounds (11.5 to 34.5 centimeter-kilograms) manually applied by a nurse or physician.

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