Method of forming an improved hydrophilic coating on a polymer s

Details Method of forming an improved hydrophilic coating on a polymer s Method of forming an improved hydrophilic coating on a polymer s

1988-08-24

1990-03-06

Rosenbaum, C. Fred

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

A61M 5325

Patent

active

049062379

ABSTRACT:
A method of forming an improved hydrophilic coating by applying on a non-reactive hydrophilic polymer surface layer an osmolality-increasing compound to produce a more stable hydrophilic surface and to produce a more slippery surface in wet condition. The polymer surface layer is treated with a solution having above 2% (weight/volume) of an osmolality increasing compound and then the solvent of the solution is evaporated. Osmolality increasing compounds are nontoxic organic or unorganic salts other than trihalogenids, mono- or di- saccharides or sugar alcohols. Preferred compounds are glucose, sorbitol, sodium chloride, sodium citrate, sodium bensoate, calcium chloride, potassium chloride, potassium iodide, potassium nitrate. The solution of the osmolality increasing compound contains preferably a polymer. Medical articles treated with the solution of osmolality increasing compounds according to the method above also relate to the invention.

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March, Jerry, Advanced Organc Chemistry, 1977, 2nd Edition, pp. 170-179.

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