Surgery – Respiratory method or device – Means for mixing treating agent with respiratory gas
Reexamination Certificate
2009-05-22
2011-12-13
Douglas, Steven (Department: 3771)
Surgery
Respiratory method or device
Means for mixing treating agent with respiratory gas
C128S200140, C424S046000
Reexamination Certificate
active
08074644
ABSTRACT:
The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000° C./s, thereby forming an vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10μ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.
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Hale Ron L.
Hodges Craig C.
Lloyd Peter M.
McKinney Jeffrey A.
Mufson Daniel
Alexza Pharmaceuticals, Inc.
Douglas Steven
Swanson & Bratschun L.L.C.
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