Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1992-10-15
1994-02-01
Saunders, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435967, 436520, 436536, 436538, 436805, 424 11, 356 39, G01N 3308, G01N 33536
Patent
active
052831787
ABSTRACT:
The type of a blood specimen is determined by adding a portion thereof, either a diluted solution of its red cells or a portion of its plasma, to each of a multiplicity of wells in a transparent tray, by adding a blood type specific reagent to each of the wells in the tray, different reagents being added to different ones of the wells of the tray, periodically tilting the tray at a substantial angle of at least approximately 50.degree. to opposite sides of a horizontal position to enhance any agglutination reaction which may be developing within any of the wells of the tray as a result of a match between the reagent and a blood type characteristic antigen or antibody in the portion of the blood specimen, and sensing each of the wells of the tray for the presence of an agglutinate therein by directing a light source through the wells, preferably from below the tray, a well with an agglutinate therein allowing more light from the light source to pass through the center thereof than a well without such an agglutinate therein. The agglutination enhancement technique of such blood specimen typing method is also applicable to other blood testing methods which rely on an agglutination reaction.
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Kessler Marsha A.
Prewitt Patricia L.
Abbott Laboratories
Bidwell Carol E.
Porembski Priscilla E.
Saunders David
Ungemach Frank s.
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