Method of fluorescent detection of nucleic acids and cytoskeleto

Details Method of fluorescent detection of nucleic acids and cytoskeleto Method of fluorescent detection of nucleic acids and cytoskeleto

1995-05-30

1997-01-14

Owens, Amelia

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

544333, 5483154, 549491, C07D40500

Patent

active

055941389

ABSTRACT:
Disclosed is a method of fluorescent detection of a nucleic acid. The method comprises contacting to the nucleic acid a bis-dicationic aryl furan compound, such as 2,5-bis[4-(4,5,6,7-tetrahydro-1H-1,3-diazepin-2-yl) phenyl] furan; 2,5-bis{[4-(N-isopropyl) amidino] phenyl}furan; and physiologically acceptable salts thereof, and exposing the nucleic acid to light at a frequency to induce fluorescence of the compound. A method for fluorescent detection of cytoskeleton elements, and novel bis-dicationic aryl furan compounds are also disclosed.

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