Method of filtering viruses from a factor VIII solution

Details Method of filtering viruses from a factor VIII solution Method of filtering viruses from a factor VIII solution

2005-11-22

2005-11-22

Weber, Jon (Department: 1653)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

C530S384000, C530S412000, C530S414000, C530S415000, C530S416000, C530S417000, C530S418000, C530S419000, C530S420000, C530S422000, C530S427000, C530S830000, C530S831000, C435S236000, C435S238000, C435S239000, C514S802000, C514S834000

Reexamination Certificate

active

06967239

ABSTRACT:
Method for preparing a factor VIII solution that is essentially free of viruses and essentially devoid of vWF (von Willebrand factor) and factor VIII-vWF complexes by (a) obtaining a starting factor VIII solution devoid of factor VIII-vWF complexes; and (b) filtering the solution through a hydrophilic virus filter.

REFERENCES:
patent: 4758657 (1988-07-01), Farb et al.
patent: 5371195 (1994-12-01), Grandgeorge et al.
patent: 5677162 (1997-10-01), Zou et al.
patent: 5869617 (1999-02-01), Fischer et al.
patent: 5892005 (1999-04-01), Fischer et al.
patent: 197 554 (1986-10-01), None
patent: 383 645 (1991-08-01), None
patent: 468 181 (1992-01-01), None
patent: 91/18017 (1991-11-01), None
patent: 96/00237 (1996-01-01), None
patent: WO 96/00237 (1996-01-01), None
patent: WO 98/37086 (1998-08-01), None
Josic et al., J. Chromatogr. B. Biomed. Appl., vol. 662, No. 2, pp. 181-190, 1994.
BMM Process Filter,PLANOVA™, Validatable Virus Removable Filters, Asahi Chemical Industry Co., Ltd., Tokyo, Japan, printed Jan. 1996.
Furlan, M. et al., “Triplet structure of von Willebrand factor reflects proteolytic degradation of high molecular weight multimer,” Proc. Natl. Acad. Sci., vol. 90, Aug. 1993, pp. 7503-7507.
De Romeuf, C. et al., “Heparin binding assay of von Willebrand factor (vWF) in plasma milieu—evidence of the importance of the multimerization degree of vWF,”(Abstract).

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