Method of fabrication of a micro-channel based integrated...

Semiconductor device manufacturing: process – Making device or circuit responsive to nonelectrical signal – Chemically responsive

Reexamination Certificate

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C438S050000, C438S052000

Reexamination Certificate

active

06933164

ABSTRACT:
A method for fabricating a sensor for chemical and/or biological materials, comprising steps of providing a wafer comprising a plurality of cantilever assemblies, each of the assemblies comprising a cantilever member and a micro-channel plate bonded to the cantilever member, the micro-channel plate further comprising a micro-channel, functionalizing each of the cantilevers by directing a flow of a plurality of functionalizing materials through the micro-channels, and dicing the wafer into a plurality of the sensors. Each of the cantilever assemblies comprises substrate comprising control and sense electrodes deposited on its top side and scribe marks etched on its back side; a cantilever member comprising a cantilever, a seed layer and a contact pad formed on top side of the cantilever member; and the micro-channel plate comprises a micro-channel housing defining the micro-channel etched through the housing, wherein the back side of the cantilever member is bonded to the substrate and the micro-channel plate is bonded to said top side of the cantilever member. Control electronics are incorporated into the substrate for a completely integrated design.

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Ilic, B., et al., “Mechanical Resonant Immunospecific Biological Detector,”Appl. Phys. Lett., vol. 77, No. 3, pp 450-452 (Jul. 17, 2000.).
Maute, M., et al., “Detection of Volatile Compounds (VOCs) with Polymer Coated Cantilevers: Changes in Resonances of Thermal Noise,”Transducers, pp 636-639 (Jun. 1999).

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