Method of fabricating capillary electrophoresis separation chann

Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge

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Details

204299R, 264313, 264317, G01N 2728, B29C 3902

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active

048161233

ABSTRACT:
The basic concept of this invention involves the use of a wire or capillary tube as a template strand. The outside diameter and shape of the template strand correspond to the inside diameter and shape of a desired separation capillary. A detector may be incorporated by providing a pair of electrode wires, or the ends of a pair of optical fibers, and pressing them against opposite sides of the template. As plastic is then polymerized around this asssembly by casting or molding. The template is then removed, leaving a capillary channel with a sidewall incorporating the wire electrodes and optical fibers. Using this method, it is possible to form a single unit including a separation capillary, conductivity detector, and spectroscopy detector.

REFERENCES:
patent: 240459 (1981-04-01), Quinby
patent: 805260 (1905-11-01), Callan
F. Foret et al., "On-line fiber optic UV detection cell and conductivity cell for capillary zone electrophoresis", Electrophoresis 1986, 7, pp. 430-432.

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