Method of fabricating bio-chip arrays

Details Method of fabricating bio-chip arrays Method of fabricating bio-chip arrays

1998-10-19

2000-04-11

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 71, 435174, 4352852, 4352872, 536 221, 536 231, 536 243, 536 2431, 536 2432, 536 2433, 367153, 367155, 437 1, C12Q 168, C12N 1100, C07H 1900, H04R 102, H01L 5140

Patent

active

060486996

ABSTRACT:
A method of fabricating one or more arrays of bio-molecule test sites including providing a solution containing bio-molecule probes in contact with the surface of a substrate, using orthogonal acoustic waves to concentrate the bio-molecule probes at a node intersection, bonding the bio-molecule probes on the substrate at the node intersection to form a test site, and removing the solution leaving the bio-molecule probes attached to the surface at the test site. The steps are repeated as often as desired, using different bio-molecule probes, to produce one or more arrays of test sites.

REFERENCES:
Yang et al Analytica chimica Acta vol.346 pp. 259-275, 1997.

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