Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1986-02-12
1987-01-20
Therkorn, Ernest G.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
62124, 62532, 210179, 210774, 210927, 210737, 422 44, 424101, 530383, 530830, A23J 106, B01D 1700, C07K 326
Patent
active
046380485
ABSTRACT:
Cryoprecipitate for the production of factor VIII is extracted from frozen blood plasma by continuously circulating the plasma in a crushed state between the peripheral and central regions of an externally, steadily heated thawing zone, with thawed mixture of liquor and cryoprecipitate being removed from the lowermost region of the zone by way of a path including a weir configuration. Preferably: the zone is formed by an axially upright cylindrical vessel; circulation is effected by at least one helical blade coaxially rotatable in the vessel, which blade extends over the vessel heights, is radially narrow compared to the vessel, is close to the vessel wall, and scoops material upwardly; the outlet from the vessel is tangentially opposed to the blade rotation; and heating is by way of a liquid jacket with generally axial flow therethrough.
REFERENCES:
patent: Re27359 (1972-05-01), Ilg
patent: 2617273 (1952-11-01), Findlay
patent: 2823242 (1958-02-01), McKay
patent: 2910516 (1959-10-01), Rush
patent: 3289838 (1966-12-01), Garrett
patent: 3527572 (1970-09-01), Urkiewicz
patent: 4066549 (1978-01-01), Oeser
patent: 4067863 (1978-01-01), Watt
patent: 4141887 (1979-02-01), Seufert
patent: 4170590 (1979-10-01), Stephan
patent: 4379083 (1983-04-01), Falke
"Thaw-Siphon Technique for Production of Cryoprecipitate Concentrate Factor VIII", by E. C. Mason, Lacet, Jul. 1, 1978, pp. 15-17.
Comment on "Thaw-Siphon Technique", by Foster and White, Lancet, Sep. 9, 1978, p. 574.
"Evaluation of the `Mason`, (Continuous-Thaw-Siphon), Method for Cryoprecipitate Production", by Prowse and McGill, vox Sanguinis, 37:235-243 (1979).
"Large Scale Plasma Thawing for Factor VIII Recovery", by Foster, Hunter, Dickson and White, Thrombosis Haemostasis 42, 64 (1979).
National Research Development Corporation
Therkorn Ernest G.
LandOfFree
Method of extracting cryoprecipitate from frozen blood plasma does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of extracting cryoprecipitate from frozen blood plasma, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of extracting cryoprecipitate from frozen blood plasma will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2135309