Method of expressing alpha-1-antitrypsin in yeast

Details Method of expressing alpha-1-antitrypsin in yeast Method of expressing alpha-1-antitrypsin in yeast

1986-12-30

1989-06-13

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

435 70, 4351723, 435255, 435256, 435320, 4351721, 536 27, 935 28, 935 37, 935 56, 935 69, C12N 500, C12N 1500, C12P 2100

Patent

active

048392839

ABSTRACT:
A method is provided for expressing human alpha-1-antitrypsin in yeast utilizing a wild-type strain and a hyperproduction mutant, GK100.

REFERENCES:
patent: 4599311 (1986-07-01), Kawasaki
Kurachi et al, Proc. Natl. Acad. Sci., vol. 78, No. 11, Nov. 30, 1981, "Cloning and Sequence of a cDNA Encoding for .alpha.-1-Antitrypsin".
Chandra et al, Biochem. Biophys. Res. Comm., vol. 103 (2), Nov. 30, 1981, "Induction of .alpha.-1-Antitrypsin mRNA and Cloning of its cDNA".
Woo et al, Miami Winter Symp., vol. 19, from Jan. 1982, p. 579, Gene to Protein: Translation into Biotechnology.
Schochat et al, J. Biol. Chem., vol. 253 (16), Aug. 25, 1975, pp. 5630-5634, "Primary Structure of Human .alpha.-1-Protease Inhibitor".
Hitzeman et al, Nature, vol. 293, Oct. 29, 1981, pp. 717-723, "Expression of a Human Gene for Interferon in Yeast".
Alber et al, J. Mol. Appl. Genet., vol. 1, pp. 419-434, 1982, "Nucleotide Sequence of the Triose Phosphate Isomerase Gene of Saccharomyces cerevisiae".
Beggs, Nature, vol. 275, pp. 104-109, Sep. 14, 1978, "Transformation of Yeast by a Replicarry Hybrid Plasmid".
Broach et al, Gene, vol. 8, pp. 121-133, 1979.
Urdea et al., "Chemical Synthesis of a Gene for Human Epidermal Growth Factor Urogastrone and Its Expression in Yeast", Proc. Natl. Acad. Sci., USA, vol. 80, pp. 7461-7465 (Dec. 1983).
Holland et al., "The Primary Structures of Two Yeast Enolase Genes", J. Biol. Chem., vol. 256, pp. 1385-1395 (1981).
Holland et al., "Structural Comparison of Two Nontandenity Repeated Yeast Glyceraldehyde-3-Phosphate Dehydrogenase Genes", J. Biol. Chem., vol. 255, No. 6, pp. 2596-2605 (Mar. 1980).
Kelly et al., "Effect of Transfer RNA from Various Sources on Placental Messenger RNA Translation", Mol. Cell. Endocrin., 29, 181-195 (1983).
Ukemura, "Correlation Between the Abundance of Yeast Transfer RNAs and the Occurrence of Respective Codons in Protein Genes", J. Mol. Biol., 158, 573-597 (1982).
Rogers et al., "The Isolation of a Clone for Human Alpha-1-Antritrypsin and the Detection of Alpha-1-Antitrypsin in mRNA from Liver and Leukocytes", Biochem. Biophys. Res. Comm., 16: 375-382 (1983).
Valenzuela et al., Nature, vol. 298, 22 Jul. 1982, "Synthesis and Assembly of Hepatitis B Surface Antigen Particles in Yeast" pp. 347-350.
Ammerer et al, Recombinant DNA Proc. 3rd Cleveland Symp. Micromol., ed. Walton, pp. 185-197, 1981.
Clifton et al., Biochemistry, 21 (8), Apr. 13, 1982, pp. 1935-1942.
Kawasaki et al., Biochem. and Biophys. Res. Comm., 108 (3), Oct. 15, 1982, pp. 1107-1112.
Carlson et al., FEBS Letters, 130 (2), Aug. 1981, pp. 297-300.
Leicht et al., Nature, 297, Jun. 24, 1982, pp. 655-659.

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