Method of evaluating immune system response to allografts, viral

Details Method of evaluating immune system response to allografts, viral Method of evaluating immune system response to allografts, viral

1987-08-20

1990-09-25

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 7, 435 29, 436 87, 436518, 436536, 436811, G01N 33543, G01N 33569

Patent

active

049593021

ABSTRACT:
Detection of solublen Interleukin-2 (IL-2) and Interleukin-2 receptor (IL-2R) levels in the serum, plasma, urine and bile of kidney and liver transplant patients using sensitive immunoassays provides valuable prognostic, monitoring and diagnostic information about impending, acute and chronic or recovering allograft rejection episodes. Additionally, monitoring immune system activation with these sensitive immunoassays can be useful for detecting viral and other infections and for distinguishing cyclosporine toxicity from graft rejection.

REFERENCES:
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Southern et al, J. Heart Transplant., 5, (No. 5), 370, Abstr. No. 29, 1987.

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