Method of enhancing the host defense

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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536 551, A61K 3170

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active

047255854

ABSTRACT:
The invention relates to a method of enhancing or regulating the host defense of a mammal, said method comprising administering to a mammal a therapeutically effective amount of hyaluronic acid.

REFERENCES:
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Hakansson et al., Reprint from "The Jour. of Clinical Investigation", vol. 66, No. 2, pp. 298-305, Aug. 1980.
Rydell, N., et al., Effect of Intra-Articular Injection of Hyaluronic Acid on the Clinical Symptoms of Arthritis in Track Horses, published in Acta Vet. Scand., vol. 11, pp. 139-155, (1970).
Algvere, P., Intravitreal Implantation of High-Molecular Hyaluronc Acid in Surgery for Retinal Detachment, published in Acta Ophthalmologica, vol. 49, pp. 975-976, (1971).
Rydell, N., et al., Effect of Intra-Articular Injection of Hyaluronic Acid on the Clinical Symptoms of Osteoarthritis and on Granulation Tissue Formation, published in Clin. Orthop., vol. 80, pp. 25-32, (1971).
Constable, Ian J., et al., Biological Vitreous Substitutes, published in Archives of Ophthalmology, vol. 88, pp. 544-548, (1972).
Balazs, E. A., et al., Hyaluronic Acid and Replacement of Vitreous and Aqueous Humor, published in Modern Problems in Ophthalmology, vol. 10, pp. 3-21, (1972).
Peyron, Jacques G., et al., Preliminary Clinical Assessment of Na-Hyaluronate Injection into Human Arthritic Joints, published in Path. Biol., vol. 22, pp. 731-736, (1974).
Rydell, N., Decreased Granulation Tissue Reaction After Installment of Hyaluronic Acid, published in Acta Orthop. Scandinav., vol. 41, pp. 307-311, (1970).
Balazs, E. A., et al., The Effect of Hyaluronic Acid on Fibroblasts, Mononuclear Phagocytes and Lymphocites, Papers of the Symposium Held in Torku, Finland, (1972).
Kulonen, E. and Pikkarainen, J., (Ed.): Biology of the Fibroblast. I, London Academic Press, p. 237, (1973).

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