Method of enhancing bioavailability of pharmaceutical agents

Details Method of enhancing bioavailability of pharmaceutical agents Method of enhancing bioavailability of pharmaceutical agents

1995-06-07

1997-03-18

Haley, Jacqueline

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3140

Patent

active

056123671

ABSTRACT:
The invention provides a pharmaceutical composition comprising a particular physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-methoxy benzoyl]-2-methylbenzenesulphonamide and polyvinylpyrrolidone. It also provides methods for preparing this physical form, and another physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-methoxy benzoyl]-2-methylbenzenesulphonamide useful in the preparation of the first mentioned physical form. The compositions are useful in the treatment of diseases in which leukotrienes are implicated, for example asthma.

REFERENCES:
T. S. Kondrat'eva, The Technology of Therapeutic Forms, Meditsina, 1991, pp. 85-88, (and translation thereof).
I. M. Rabinovich, The Use of Polymers in Medicine, Leningrad Meditsina, 1972, pp. 16-17, (and translation thereof).

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