Method of encapsulating anthracycline in liposomes

Details Method of encapsulating anthracycline in liposomes Method of encapsulating anthracycline in liposomes

1994-09-28

1996-10-01

Venkat, Jyothsna

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

264 41, 264 46, A61K 9127

Patent

active

055609236

ABSTRACT:
A method of preparing a liposomal anthracycline glycoside composition, which entails forming cardiolipin-containing liposomes by drying a lipid mixture containing cardiolipin, and then introducing an aqueous solution, and mixing the cardiolipin-containing liposomes with a solution of anthracycline glycoside.

REFERENCES:
patent: 4419348 (1983-12-01), Rahman et al.
patent: 4898735 (1990-02-01), Barenholz et al.
patent: 4906477 (1990-03-01), Kurono et al.

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