Chemistry: analytical and immunological testing – Peptide – protein or amino acid – Glycoproteins
Reexamination Certificate
2004-02-02
2008-10-21
Wallenhorst, Maureen M (Department: 1797)
Chemistry: analytical and immunological testing
Peptide, protein or amino acid
Glycoproteins
C436S063000, C436S065000
Reexamination Certificate
active
07439071
ABSTRACT:
A method of determining the presence of preeclampsia is provided wherein a determination is made as to whether there has been a substantial elevation in marinobufagenin which may be a blood-derived or urine-derived and if such elevation does exist concluding that preeclampsia does exist in a patient. The method may advantageously be practiced by employing urine, blood serum or blood plasma as the body specimen containing the protein in determining whether a patient has preeclampsia. The method may include subsequent therapeutic patient treatment. Related diagnostic apparatus is also provided.
REFERENCES:
patent: 5079171 (1992-01-01), Senyei et al.
patent: 5543138 (1996-08-01), Keith
patent: 5770376 (1998-06-01), Bagrov
patent: 2003/0044856 (2003-03-01), Puschett
patent: 2006/0134106 (2006-06-01), Adair
Bagrov, Alexei Y., et al., “Characterization of a Urinary Bufodienolide Na+, K+-ATPase inhibitor in Patients After Acute Myocardial Infarction,” Hypertension, vol. 31, No. 5, pp. 1097-1103, May 1998.
Chen, Tai C., et al., “Volume Expansion-Induced Changes in Renal Tubular Membrance Protein Phosphorylation,” Biochemical and Biophysical research Communications, vol. 143, No. 1, pp. 74-80, Feb. 1987.
Lopatin, D.A. et al., “Circulating Bufodienolide and Cardenolide Sodium Pump Inhibitors in Preeclampsia,” Journal of Hypertension, 1999, vol. 17, No. 8, pp. 1179-1187.
Khedun, S.M. et al., “Drug Management of Hypertensive Disorders or Pregnancy,” Pharmacol. Ther., 1997, vol. 74, No. 2, pp. 221-258.
Eckert Seamans Cherin & Mellott , LLC
Marmo Carol A.
Silverman Arnold B.
The Administrators of the Tulane Educational Fund
Wallenhorst Maureen M
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