Method of drug detection

Chemistry: analytical and immunological testing – Nuclear magnetic resonance – electron spin resonance or other...

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250282, 250287, 436175, 436178, 436181, 436901, G01D 3000, G01D 3394

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049886282

ABSTRACT:
Disclosed are methods of rapidly and accurately detecting a compound-of interest, such as a toxic drug, in a body fluid. A liquid sample containing various native constituents and an anticipated exogenous chemical compound is obtained from the body. The sample is then subjected to analysis by ion mobility spectrometry to determine the presence of the exogenous chemical compound or related metabolite therein. The method may further include the step of separating the compound-of-interest from said native constituents in said fluid sample prior to analysis.

REFERENCES:
patent: 4194884 (1980-03-01), Rounbehler et al.
patent: 4468468 (1984-08-01), Benninghoven et al.
patent: 4472631 (1984-09-01), Enke et al.
patent: 4633083 (1986-12-01), Knorr et al.
patent: 4698071 (1987-10-01), Elias
patent: 4732046 (1988-05-01), Lawrence et al.
patent: 4754135 (1988-06-01), Jackson
patent: 4769540 (1988-09-01), Mitsui et al.
patent: 4774408 (1988-09-01), Gohlke
patent: 4777363 (1988-10-01), Eiceman et al.
patent: 4778993 (1988-10-01), Waugh
patent: 4797554 (1989-01-01), Blanchard et al.
Huber, J. F., Matisova, E., Kenndler, E., "Effects of Column Parameters on Optimization of Gas Chromatography/Mass Spectrometry" Anal. Chem., 1982, vol. 54, pp. 1297-1304.
Brunnee, C., "Deflection of Charged Particles in Magnetic Fields," Spectra, vol. 9, Nos. 2 and 3, 1983, pub. Finnigan MAT.
Settlage, J.; Jaeger, H.; "Advantages of Fused Silica Capillary Gas Chrometography for GC/MS Applications", J. of Chromatographic Science, vol. 22, May 1984, pp. 192-197.
Lawrence, A. H.; "Characterization of Benzodiazepine Drugs by Ion Mobility Spectrometry", Anal. Chem. 1989, vol. 61 (4), Feb. 15, 1989, pp. 343-348.
Jolley et al. (1981) Clin. Chem. 27/9:1575-1579.
Lawrence (1986) Analytical Chemistry, 58 No. 6:1069-1272.
Caplan et al. (1987) Clin. Chem. 33/7:1200-1202.
Lawrence (1987) Forensic Science International, 34:73-83.
Nanji et al. (1987) Clinical Toxicology 25(6):501-515.
Nanji et al., (1988)International Journal of Clinical Pharmacology, Therapy and Toxicology, 26 No. 1:1-3.

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