Surgery – Miscellaneous – Methods
Patent
1997-01-29
1998-07-14
Millin, V.
Surgery
Miscellaneous
Methods
436821, 436811, A61B 1900
Patent
active
057788952
ABSTRACT:
The present invention provides a method for the differential diagnosis of bacterial meningitis in an individual in need of such diagnosis, comprising the steps of: measuring the levels of complement C3 and complement factor B in the cerebrospinal fluid of the individual; and determining whether that individual has bacterial menigitis based on the levels of complement C3 and complement factor B in the cerebrospinal fluid of that individual. Also provided is a method for the differential diagnosis of bacterial menigitis in an individual in need of such diagnosis, comprising the steps of: measuring the levels of complement factor B in a sample from the individual; and determining whether that individual has bacterial menigitis based on the levels of complement factor B in the sample from that individual.
REFERENCES:
patent: 4642284 (1987-02-01), Cooper et al.
Teisner et al. "Factor I deficeincy and C3 nephritic factor" Scand J Immunol. 20:291-7, Dec. 1984.
Beatty et al. "Complement abnormalities during an epidemic of group B meningococcal infection in children" Clin exp Immunol 64:465-70, 1986.
Fernandez-Sola et al. "Persistent low C3 levels asociated with meningococcal meningitis and mebranoproliferative glomerulonephritis" Am J Nephrol 10:426-30, 1990.
Barnum et al. "Production and interferon-gamma-mediated regulation of complement compound C2 and factors B and D by the astroglioma cell line U105-MG" 287:595-601, 1992.
Bonnin et al. "Complement factor I deficeincy with recurrent aseptic meningitis" Arch intern med 153:1380-3, Jun. 1993.
Kossmann et al. "Elevated levels of the complement components C3 and factor B in ventricular cerebrospinal fluid of patients with traumatic brain injury" J. Neuroimmunol 73:63-9, 1997.
Barnum Scott R.
Stahel Phillip
Adler, J.D. Benjamin Aaron
Millin V.
O'Hara Kelly
UAB Research Foundation
LandOfFree
Method of discriminating bacterial from aseptic meningitis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of discriminating bacterial from aseptic meningitis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of discriminating bacterial from aseptic meningitis will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1872844