Method of directing transgenic expression in animals using a pro

Details Method of directing transgenic expression in animals using a pro Method of directing transgenic expression in animals using a pro

1987-08-06

1992-01-21

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

435 691, 800 2, 800DIG1, 935 11, 935 13, C12N 1500, C12P 2100

Patent

active

050827790

ABSTRACT:
A method of expressing a non-prolactin gene in a transgenic animal, said expression occurring essentially only after birth and essentially only in the pituitary cells of said animal, which comprises (a) operably linking said gene to a prolactin promoter to form a transcriptional unit, and (b) introducing said unit into one or more cells of said animal.

REFERENCES:
patent: 4579821 (1986-04-01), Palmiter et al.
patent: 4675297 (1987-06-01), Baxter et al.
patent: 4725549 (1988-02-01), Cooke et al.
Low et al., Cell 41, pp. 211-219 (1985).
Camper et al., Journal of Biological Chemistry 260(2), pp. 12246-12251 (1985).
Nelson et al., Nature 322, pp. 557-562 (1986).
Camper et al., DNA 3(3), pp. 237-249 (1984).
Van Brunt, Bio Technology 6(10); 1149, 1151, 1152, 1154 (1988).
Wilmut, New Scientist, 7 Jul. 1988, pp. 56-59.
Slabaugh et al., Endocrinology 110(5):1489-1497 (1982).
Hoeffler et al., Endocrinology 117(1):187-195 (1985).
Salter, et al., Transgenic Chickens:Insertion of Retroviral Genes into the Chicken Germ Line Virology, 157:236-240 (1987).
Zuoyan, et al., Biological Effects of Human Growth Hormone Gene Microinjected into the Fertilized Eggs of Loach, Kexye Tongbau 31:988-990 (1986).
MacLean, et al., Introduction of Novel Genes into Fish, Bio/Technology 5:257-261 (1987).
Rusconi, et al., Transformation of Frog Embryos with a Rabbit .beta.-globin Gene, Proc. Natl. Acad. Sci. 78:5051-5055 (1981).
Kawade et al., Biol. Interferon Syst., Proc. ISIR-INO Meet., Interferon Syst., 305-311 (1986), Transgenic Mice Carrying Exogenous Mouse Interferon Genes.
Palmiter, R. and Brinster, R., Ann. Rev. Genet. 20:465-99 (1986), Germ-Line Transformation of Mice.
Khillan et al., Proc. Natl. Acad. Sci. 83:725-29 (Feb. 1986), Developmental and Tissue-Specific Expression Directed by the Alpha.sub.2 Type I Collagen Promoter . . .
Overbeek et al., Proc. Natl. Acad. Sci. 82:7815-19 (Dec. 1985), Lens-Specific Expression and Developmental Regulation of the Bacterial Chloramphenicol . . .

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