Method of differentiating pelvic inflamatory disease and local i

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435912, 536 231, 536 237, 536 2432, 536 2433, 935 6, 935 77, 935 78, C12Q 168, C12P 1934, C07H 2104

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058244808

ABSTRACT:
The present invention provides a method of differentially diagnosing pelvic inflammatory disease from local infection of Neisseria gonorrhoeae in an individual, comprising the step of identifying whether the individual carries a strain of Neisseria gonorrhoeae which is stable resistant to the bacteriocidal effects of normal human serum. Also provided is a method of differentially diagnosing pelvic inflammatory disease from local infection of Neisseria gonorrhoeae in an individual, comprising the step of determining the presence of a 344 base pair DNA sequence from the 2.2 kb sac-4 region of Neisseria gonorrhoeae in a clinical isolate obtained from said individual.

REFERENCES:
Rice et al. The Journal of Immunology 124:2105-2109 (May 1980).

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