Method of diagnosing periodontal disease through the detection o

Surgery – Truss – Pad

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

128717, 128719, 424 9, A61B 500, G01N 100, G01N 3348

Patent

active

043345409

ABSTRACT:
A novel method of diagnosing periodontal disease is disclosed wherein telltale pyridine and alkyl-pyridine compounds which are detected in the oral cavity are indicative of periodontal disease. An alternate embodiment method is disclosed wherein increased concentrations of certain other compounds are detected to confirm the presence of periodontal disease.

REFERENCES:
patent: 3986494 (1976-10-01), Preti et al.
patent: 4010738 (1977-03-01), Preti et al.
patent: 4119089 (1978-10-01), Preti et al.
Tonzetich, Arch. Oral Biol., vol. 9, 1964, pp. 39-45.
Lindhe, J. Periodont. Res., vol. 2, 1967, pp. 194-198.
Zelson et al., IADR Abstracts, 1978, J. Dent. Res., vol. 57, Jan. 1978, Ab. No. 679.
Dreizen, Oral Surg., vol. 9, 1956, pp. 278-283.
Main, Brit. J. Dermat., vol. 79, 1967, pp. 20-30.
Teranishi, Analytical Chem., vol. 44, 1972, pp. 18-20.
Chen, J. Lab. & Clin. Med., vol. 75, 1970, pp. 622-627, and 628-635.
Charalambous (Ed), Analysis of Foods & Beverages, Acd. Press, N. Y., 1978, pp. 283-357.
Kostelc et al., IADR Abstrats, 1979, J. Dent. Res., vol. 58, Jan. 1979, Ab. No. 325.
Dolby (Ed), Oral Mucosa in Health & Dis., Blackwell Sci. Pub. Oxford, pp. 113-116.
Afonsky, Saliva & Its Relation to Oral Health, U. of Ala. Press, 1961, pp. 97-104.
Brunneman, Chem. Abs., vol. 89, 1978, Ab. No. 89:194115x.
Golub, J. Periodont. Res., vol. 6, 1971, pp. 243-251.
Loe, Acta Odont. Scand., vol. 21, 1963, pp. 533-549.
Rizzo, Periodontics, vol. 5, No. 5, 1967, pp. 233-236.
Lindhe, J. Perodont. Res., vol. 3, 1968, pp. 12-20.
Miles, Brit. Dent. J., vol. 105, No. 7, 1958, pp. 235-248.
McNamara, Oral Surg., vol. 34, Jul. 1972, pp. 41-48.
Loe, J. of Periodont., vol. 36, 1965, pp. 37/209-45/217.
Grant, WHM, Toxicology of the Eye, C. C. Thomas, Pub., 1962.
Lorber, Am. Rev. Respiratory Dis., vol. 112, 1975, pp. 875-876.
Berg, J. Dent. Res., vol. 26, 1947, pp. 67-71.
Law, J. Dent. Res., vol. 22, 1943, pp. 373-379.
Ramfjord, J. Periodont., vol. 30, 1959, pp. 51-59.
Tonzetich, J. Int. Med. Res., vol. 6, 1978, pp. 245-254.
Tonzetich, Archs. Oral Biol., vol. 16, 1971, pp. 587-597.
Thompson, Analytical Chem., vol. 47, Jul. 1975, pp. 1313-1321.
Tonzetich, J. Periodont., vol. 48, 1977, pp. 13-20.
Rao, J. Dent. Res., vol. 57(A), 1978, p. 244, Ab. No. 680.
Labows, J. of Chromat. Biomed. Applications, vol. 163, 179, pp. 294-299.
Tonzetich, Int. Dent. J., vol. 28, 1978, pp. 309-319.
Doty, R., "Procedure for Combining Menstrual Cycle Date", Journal of Clinical Endocrinology & Metabolism, vol. 48, No. 6, Jun. 1979, pp. 912-918.
Watson, Analytical Chem., vol. 37, Jun. 1965, pp. 844-851.
Moss, C. W. and S. B. Dees, "Cellular fatty acids and metabolic products of Pseudomonas species obtained from clinical specimens"; Journal of Clinical Microbiology 4: 492-502 (1976).
Wade, T. J. and R. J. Mandel, 1974, "New gas Chromatographic characterization procedure": preliminary studies on some Pseudomonas species Applied Microbiology 27: 303-311, Feb. 1974.
Tonzetich, Oral Surg., vol. 42, 1976, pp. 172-181.
Charles D. Cox and J. Parker, "Use of 2-aminoacetophenone production in identification of Pseudomonas aeruginosa", Journal of Clinical Microbiology, Apr. 1979, 9: 479-484.
Hayward et al., "Development of specific tests for rapid detection of E. coli and species of Proteus in urine", Journal of Clinical Microbiology, Sep. 1977, 6: 195-201.
Van den Dool, J. of Chromat., vol. 11, 1963, pp. 463-471.
Miller et al., "Volatile Compounds Produced in Sterile Fish (Sebastes malanops) by Pseudomonas putrefaciens, Pseudomonas fluorescens, and an Achromobacter Species", Applied Microbiology, 26: 18-21, Jul. 1973.
Lee et al., "High resolution gas chromatographic profiles of volatile organic compounds produced by microorganisms at refrigerated temperatures", Applied and Environmental Microbiology No. 1 37: 85-90, Jan. 1979.
Tonzetich, Archs. Oral Biol., vol. 23, 1978, pp. 875-880.
Brunn et al., "Epidemiology of Pseudomanas aeruginosa infections: determination by Pyocin typing", Journal of Microbiology, 3: 264-271 (1976).
Laraya-Cuasay et al., "Pseudomonas carrier rates of patients with cystic fibrosis and of members of their families", Journal of Pediatrics, 89: 23-26 (1980).
Tonzetich, Archs. Oral. Biol., vol. 14, 1969, pp. 815-827.
Mitruka, "Gas chromatography application in microbiology and medicine", (1979), John Wiley & Sons, New York, Chapter 13, 352-374.
Brooks et al., "Further studies on the differentiation of Clostridium sordelli from Clostridium bifermentans by gas chromatography", Canadian Journal of Microbiology 16: 1071-1078 (1970).
Holzer, J. of Chromat., vol. 142, 1977, pp. 755-764.
"Analysis by gas chromatography of fatty acids found in whole cultural extracts of Neisseria species", Can. J. Microbiol. 17: 531-541 (1970).
Brooks et al., "Analysis by gas chromatography of hydroxy acids produced by several species of Neisseria", Canadian Journal of Microbiology 18: 157-168 (1972).
Golub, Oral Sci. Rev., vol. 8, pp. 49-61.
Kostelc et al., "Salivary volatiles as indicators of periodontitis", J. Periodont. Res. 18: 185-192 (1980).
Matsumota et al., "Identification of volatile compounds in human urine", J. Chromatogr. 85: 31-34 (1973).
Rooth, The Lancet, II, 19 Nov. 1966, pp. 1102-1105.
Zlatkis et al., "Concentration and analysis of volatile urinary metabolites", J. Chromatogr. Sci. 11: 299-302 (1973).
Reiner et al., "Botulism: A pyrolysis-gas-liquid chromatographic study", J. Chromatogr. Sci. 16: 623-629 (1978).
Russell, J. Dent. Res., vol. 35, 1956, pp. 350-359.
Bohannon et al., "Quantitative methods for the gas chromatographic characterization of acidic fermentation by-products of anaerobic bacteria", J. of Chromatogr. Sci. 16: 28-35 (1978).
Larsson et al., "Analysis of Amines and other bacterial products by head-space gas chromatography", Acta Path. Microbiol. Scand. Section B 86: 207-213 (1978).
Simenhoff, N. E. J. Med., vol. 297, 1977, pp. 132-135.
Hayward et al., "Methylmercaptan and DMDS production from methionine by Proteus Species Detected by Head-Space Gas-Liquid Chromatography", J. of Clin. Microbiol. 6: 187-194 (1977).
Labows et al., "Characteristic Gamma-Lactone odor production of the genus Pityrosporum", Appl. and Environ. Micro. 38: 412-415 (1979).
Sicher(ed) Orban's Oral Histology & Embryology, Mosby, St. Louis, 1972, pp. 269-271.
Morgan, "The chemistry of some microbially-induced flavor defects in milk and dairy foods", Biotech. Bioeng. 18: 953-965 (1976).
Liebich et al., "Volatile substances in blood serum: profile analysis and quantitative determination", J. Chromatogr. 142: 505-516 (1977).
Holm-Pedersen, J. Periodont. Res., vol. 2, 1967, pp. 13-20.
Withycombe et al., "Isolation and identification of volatile components from wild rice grain", J. of Agricultural Food Chemistry, vol. 6, pp. 816-821, (1978).
Budzikiewicz et al., "Mass spectrometry of organic compounds", p. 155, Holden-Day, Inc., San Francisco (1967).
Iusem, Oral Surg., vol. 3, 1950, pp. 1516-1520.
Dwivedi et al., "Carbonyl production from lipolyzed milk fat by the continuous mycelial culture of Penicillium roqueforti", J. Food Science, 39: 83-137 (1974).
Burger et al., "Ketones from the pedal gland of the bontebok", Z. Naturforsch C: Bioscience, 316: (1-2): 21-28 (1976).
Hafez(ed), The Human Vagina, North-Holland Pub., N. Y., 1978, pp. 151-166.
Albone et al., "Bacteria as a source of chemical signals in Mammals", reprinted pp. 35-43 in D. MullerSchwarze & M. M. Mozell, Editors, Chemicals Signals in Vertebrates, Plenum Press, N.Y. (1977).
Ikeshoji, "Bacterial production of the ovipositional attractants for mosquitos on fatty acid substrates", App. Ent. Zool. 10: 239-242, (1975).
Jellum, Analytical Chem., vol. 45, 1973, pp. 1099-1106.
Labows et al., "Headspace Analysis of Volatile Metabolites of Pseudamonas aerugino and Related Species by Gas Chromatography-Mass Spectrometry", J. Clin. Microbiol., vol. 12, Oct. 1980, pp. 521-526.
Gorbach, S. L., J. W. Mayhew, J. G. Bartlett, II. Thadepalli, and A. B. Onderdonk. Rapid Diagnosis of anaerobic infections by direct gas-liquid chromatography of clinical specimens, J. Clin. Invest. 57: 478-484, (1976).
Hutterer

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of diagnosing periodontal disease through the detection o does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of diagnosing periodontal disease through the detection o, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of diagnosing periodontal disease through the detection o will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1915103

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.