Method of diagnosing nephrotic syndrome

Details Method of diagnosing nephrotic syndrome Method of diagnosing nephrotic syndrome

2007-11-20

2007-11-20

Le, Long V. (Department: 1641)

Chemistry: analytical and immunological testing

Test for named disease, body condition or organ function

C435S007100, C435S007920, C436S174000

Reexamination Certificate

active

10487978

ABSTRACT:
This invention provides organic biomolecule markers (e.g., proteins) useful for differentiating minimal change nephrotic syndrome (MCNS) from focal segmental glomerulosclerosis (FCS), membranous nephrothropy (MN), and membranoproliferative glomerulonephritis (MPGN). This invention also provides organic biomolecule markers useful for evaluating the therapeutic value of agents for treating kidney disease.

REFERENCES:
patent: 5719060 (1998-02-01), Hutchens et al.
patent: 6225047 (2001-05-01), Hutchens et al.
Akhoundi et al., Production and Characterization of monoclonal and polyclonal antibodies to human alpha-2-HS: development of a two-site ELISA test, Journal of Immunological Methods 172 (1994), pp. 189-196.
Lebreton et al., Serum concentation of Human Alpha 2-HS glycoprotein during the inflammatory process, J. Clin. Invest., vol. 64, Oct. 1979, pp. 1118-1129.

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