Chemistry: analytical and immunological testing – Measurement of electrical or magnetic property or thermal... – Of a liquid
Patent
1987-10-19
1989-03-07
Castel, Benoit
Chemistry: analytical and immunological testing
Measurement of electrical or magnetic property or thermal...
Of a liquid
436149, 436151, 436174, 424 88, 128734, 128637, A61K 3900, G01N 2508, G01N 100, A61B 500
Patent
active
048106577
ABSTRACT:
Multiple sclerosis and other diseases are diagnosed by first coating a plasm protein-adsorbing surface with a patient's blood plasm protein in an electrolyte fluid, and measuring the streaming potential of the protein-coated surface. Next, a challenge material such as a fatty acid having from 6 to 24 carbon atoms is added to the protein in electrolyte fluid mixture to alter the electro-kinetic potential of the adsorbed blood plasm protein layer. The streaming potential of the altered layer then is measured. The streaming potential results thus obtained are compared with measurements of the streaming potential characteristic of a surface similarly treated, but using normal blood plasma protein.
REFERENCES:
patent: 4294818 (1981-10-01), McMichael et al.
patent: 4311686 (1982-01-01), Angers et al.
patent: 4425922 (1984-01-01), Conti et al.
patent: 4705756 (1987-11-01), Spillert et al.
Goodwin James W.
Swank Roy L.
Alexander Lyle Alfandary
Castel Benoit
Farley Eugene D.
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