Method of diagnosing cancer susceptibility or metastatic potenti

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 911, 435 912, 536 235, 536 2431, 935 1, 935 8, 935 77, 935 78, C12Q 168, C12P 1934, C07H 2104, C12N 1500

Patent

active

057534373

ABSTRACT:
The present invention relates, in general, to a method for diagnosing cancer susceptibility based on alterations in the nm23 gene. In particular, the present invention relates to a method of identifying individuals at risk for developing a primary cancer or at risk for suffering treatment failure, morbidity, or mortality associated with cancer. The invention further relates to a means of using genetic methods to predict individuals at increased risk for developing distant metastases.

REFERENCES:
Bevilacqua et al. Cancer Research (USA), 1989, 49/18, (5185-5190); abstract only.

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