Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1994-07-29
1997-08-12
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
436 64, G01N 33574
Patent
active
056564430
ABSTRACT:
This invention relates to a method of diagnosing and screening for transitional cell carcinoma of the bladder. Urine from an individual suspected of having transitional cell carcinoma of the bladder is analyzed for the presence of an increased level of scatter factor, an increased level of scatter factor indicating that said individual has bladder cancer. This invention further relates to a method of monitoring bladder cancer activity by measuring the level of scatter factor in urine, and to a method of determining the prognosis of an individual having bladder cancer by measuring the level of scatter factor in tumor extract from the individual.
REFERENCES:
patent: 4447545 (1984-05-01), DeFazio et al.
patent: 5362716 (1994-11-01), Kmiecik et al.
Chodak et al. "Urine from Patients with Transitional-cell carcinoma stimulates migragtion of capillary endothelial cells", The New England Journal of Medicine, vol. 305, No. 15, pp. 869-874, issued 08 Oct. 1981.
Yamashita et al. "Immunoreactive Hepatocyte Growth Factor is a strong and Independent Predictor of Recurrence and Survival in Human Breast Cancer", Cancer Research, vol. 54, pp. 1630-1633, issued 01 Apr. 1994.
Goldberg Itzhak D.
Rosen Eliot M.
Weiss Gary H.
Eyler Yvonne
Long Island Jewish Medical Center
Scheiner Toni R.
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