Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1996-12-26
1999-05-18
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 71, 436 63, 436 64, 436813, 436501, G01N33/574;33/53
Patent
active
059050276
ABSTRACT:
The present invention provides a recombinant toxin and monoclonal antibody which specifically binds to glial-derived or meningioma-derived tumor cells. Also provided are various methods of screening for malignant gliomas and meningiomas. Further provided are methods of treating malignant gliomas, including glioblastoma multiforme and astrocytomas.
REFERENCES:
Ullrich, et al., Neuro Report, vol. 7, No. 5, Apr. 10, 1996, pp. 1020-1024.
Ullrich, et al., Am. J. Physiol., vol. 270, No. 5, pt. 1, 1996, pp. C1511-1521.
Sontheimer Harald W.
Ullrich Nicole
Adler Benjamin Aarovi
Scheiner Toni R.
Sun-Hoffman Lin
UAB Research Foundation
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