Method of determining the sequence of nucleic acids employing so

Details Method of determining the sequence of nucleic acids employing so Method of determining the sequence of nucleic acids employing so

1998-01-26

2000-04-04

Fredman, Jeffrey

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

34082554, 34087017, 34082506, 435 912, 435810, 435973, 436501, 436519, 436520, 536 231, 536 243, G05B 2302, G08C 1912, C07H 2104, C12Q 168

Patent

active

060460032

ABSTRACT:
A method is described for determining the sequence of nucleic acids. The method employs small solid phase particles having transponders, with a primary layer of an oligonucleotide of known sequence attached to the outer surface of the particle. A read/write scanner device is used to encode and decode data on the transponder. The stored data includes the sequence of the oligonucleotide immobilized on the transponder. The sequence of sample nucleic acids is determined by detecting annealing to an oligonucleotide bound to a particle, followed by decoding the transponder to determine the sequence of the oligonucleotide.

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